Diabetes Res Clin Pract. 2023 Jun 16:110780. doi: 10.1016/j.diabres.2023.110780. Online ahead of print. ABSTRACT AIMS: To compare body composition, visceral adiposity, adipocytokines, and low-grade inflammation markers in prepubertal offspring of mothers who were treated with metformin or insulin for gestational diabetes mellitus (GDM). METHODS: 172 offspring of 311 mothers randomized…
Author: Henok Karvonen
Neighbourhood deprivation in childhood and adulthood and risk of arterial stiffness: the Cardiovascular Risk in Young Finns study
Blood Press. 2023 Dec;32(1):2220037. doi: 10.1080/08037051.2023.2220037. ABSTRACT Purpose: Individual socioeconomic status is associated with increased arterial stiffness, but limited data are available on the relations of neighbourhood deprivation with this vascular measure. We prospectively examined whether neighbourhood deprivation in childhood and adulthood predicts arterial stiffness indicated by pulse wave velocity…
Mother-infant interaction and maternal postnatal psychological distress are associated with negative emotional reactivity among infants and toddlers- A FinnBrain Birth Cohort study
Infant Behav Dev. 2023 Jun 5;72:101843. doi: 10.1016/j.infbeh.2023.101843. Online ahead of print. ABSTRACT Studies have reported mixed findings regarding the effects of mother-infant interaction and maternal distress on children’s negative emotional reactivity. In the current study (N = 134 and 107), we examined the effects of maternal Emotional Availability (sensitivity,…
Comorbidity in congenital hypothyroidism – A nationwide population-based cohort study
J Clin Endocrinol Metab. 2023 Jun 6:dgad334. doi: 10.1210/clinem/dgad334. Online ahead of print. ABSTRACT CONTEXT: Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties. OBJECTIVE: The aim of this nationwide population-based register study was to investigate the incidence of…
Dietary patterns from youth to adulthood and cognitive function in midlife: The cardiovascular risk in Young Finns Study
Nutrition. 2023 Aug;112:112063. doi: 10.1016/j.nut.2023.112063. Epub 2023 Apr 27. ABSTRACT OBJECTIVES: Diet plays an important role in cognitive health, but the long-term association of diet early in life with cognitive function in adulthood has not, to our knowledge, been rigorously studied. The aim of this study was to examine the…
Prediction of pre-diabetes and type 2 diabetes nine years postpartum using serum metabolome in pregnant women with gestational diabetes requiring pharmacological treatment
J Diabetes Complications. 2023 Jul;37(7):108513. doi: 10.1016/j.jdiacomp.2023.108513. Epub 2023 May 26. ABSTRACT AIMS: We examined the association between serum metabolome in women with pharmacologically treated gestational diabetes (GDM) and measures of glucose metabolism 9 years postpartum. METHODS: Serum targeted metabolome, adiponectin, inflammatory markers, and insulin-like growth factor-binding protein-1 phosphoisoforms were…
Hair cortisol, cortisone and DHEA concentrations and the composition of microbiota in toddlers
Psychoneuroendocrinology. 2023 Aug;154:106309. doi: 10.1016/j.psyneuen.2023.106309. Epub 2023 May 25. ABSTRACT Animal research suggests that the gut microbiota and the HPA axis communicate in a bidirectional manner. However, human data, especially on early childhood, remain limited. In this exploratory design, we investigated the connections between long-term HPA axis functioning, measured as…
Childhood trauma and fear of childbirth: findings from a birth cohort study
Arch Womens Ment Health. 2023 May 27. doi: 10.1007/s00737-023-01328-x. Online ahead of print. ABSTRACT The aim of this study is to investigate if experiencing childhood trauma (emotional abuse, emotional neglect, physical abuse, physical neglect, or sexual abuse) or a greater total burden of childhood trauma increase the risk of fear…
Author Correction: The power of genetic diversity in genome-wide association studies of lipids
Nature. 2023 Jun;618(7965):E19-E20. doi: 10.1038/s41586-023-06194-2. NO ABSTRACT PMID:37237109 | DOI:10.1038/s41586-023-06194-2…
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis
Epigenetics. 2023 Dec;18(1):2211361. doi: 10.1080/15592294.2023.2211361. ABSTRACT BACKGROUND: Dietary intake of antioxidants such as vitamins C and E protect against oxidative stress, and may also be associated with altered DNA methylation patterns. METHODS: We meta-analysed epigenome-wide association study (EWAS) results from 11,866 participants across eight population-based cohorts to evaluate the association…
