Nature. 2023 Jun;618(7965):E19-E20. doi: 10.1038/s41586-023-06194-2. NO ABSTRACT PMID:37237109 | DOI:10.1038/s41586-023-06194-2…
Author: Henok Karvonen
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis
Epigenetics. 2023 Dec;18(1):2211361. doi: 10.1080/15592294.2023.2211361. ABSTRACT BACKGROUND: Dietary intake of antioxidants such as vitamins C and E protect against oxidative stress, and may also be associated with altered DNA methylation patterns. METHODS: We meta-analysed epigenome-wide association study (EWAS) results from 11,866 participants across eight population-based cohorts to evaluate the association…
Investigating the role of relationship satisfaction and paternal psychological distress during pregnancy on offspring health in early life
BJPsych Open. 2023 May 25;9(3):e100. doi: 10.1192/bjo.2023.59. ABSTRACT BACKGROUND: The research on the role of father in the foetal programming of health and behaviour has received increasing attention. However, the influences of paternal depressive symptoms and couple relationship satisfaction during pregnancy – potentially mediated via maternal well-being – on the…
Modifications of 24-h movement behaviors to prevent obesity in retirement: a natural experiment using compositional data analysis
Int J Obes (Lond). 2023 May 23. doi: 10.1038/s41366-023-01326-0. Online ahead of print. ABSTRACT BACKGROUND: Retirement often leads to a more passive lifestyle and may therefore lead to weight gain. This study aims to investigate longitudinal associations between changes in 24-h movement behaviors and BMI and waist circumference in relation…
Tracking of Cardiorespiratory Fitness and Physical Activity from Youth to Young Adulthood: Findings from the Prospective Special Turku Coronary Risk Factor Intervention Project (STRIP)
J Pediatr X. 2023 Feb 28;9:100085. doi: 10.1016/j.ympdx.2023.100085. eCollection 2023 Summer. ABSTRACT Using data from the Special Turku Coronary Risk Factor Intervention Project, cardiorespiratory fitness (rank-order correlation coefficient = 0.60-0.62) tracked stronger than physical activity (rank-order correlation coefficient = 0.27-0.38) between youth (age = 17 years) and young adulthood (age…
Metformin versus insulin for gestational diabetes: Adiposity variables and adipocytokines in offspring at age of 9 years
Diabetes Res Clin Pract. 2023 Jun 16:110780. doi: 10.1016/j.diabres.2023.110780. Online ahead of print. ABSTRACT AIMS: To compare body composition, visceral adiposity, adipocytokines, and low-grade inflammation markers in prepubertal offspring of mothers who were treated with metformin or insulin for gestational diabetes mellitus (GDM). METHODS: 172 offspring of 311 mothers randomized…
Neighbourhood deprivation in childhood and adulthood and risk of arterial stiffness: the Cardiovascular Risk in Young Finns study
Blood Press. 2023 Dec;32(1):2220037. doi: 10.1080/08037051.2023.2220037. ABSTRACT Purpose: Individual socioeconomic status is associated with increased arterial stiffness, but limited data are available on the relations of neighbourhood deprivation with this vascular measure. We prospectively examined whether neighbourhood deprivation in childhood and adulthood predicts arterial stiffness indicated by pulse wave velocity…
Mother-infant interaction and maternal postnatal psychological distress are associated with negative emotional reactivity among infants and toddlers- A FinnBrain Birth Cohort study
Infant Behav Dev. 2023 Jun 5;72:101843. doi: 10.1016/j.infbeh.2023.101843. Online ahead of print. ABSTRACT Studies have reported mixed findings regarding the effects of mother-infant interaction and maternal distress on children’s negative emotional reactivity. In the current study (N = 134 and 107), we examined the effects of maternal Emotional Availability (sensitivity,…
Comorbidity in congenital hypothyroidism – A nationwide population-based cohort study
J Clin Endocrinol Metab. 2023 Jun 6:dgad334. doi: 10.1210/clinem/dgad334. Online ahead of print. ABSTRACT CONTEXT: Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties. OBJECTIVE: The aim of this nationwide population-based register study was to investigate the incidence of…
Dietary patterns from youth to adulthood and cognitive function in midlife: The cardiovascular risk in Young Finns Study
Nutrition. 2023 Aug;112:112063. doi: 10.1016/j.nut.2023.112063. Epub 2023 Apr 27. ABSTRACT OBJECTIVES: Diet plays an important role in cognitive health, but the long-term association of diet early in life with cognitive function in adulthood has not, to our knowledge, been rigorously studied. The aim of this study was to examine the…
