Toxics. 2023 Mar 4;11(3):241. doi: 10.3390/toxics11030241. ABSTRACT Phthalates are mainly used as plasticizers and are associated inter alia with adverse effects on reproductive functions. While more and more national programs in Europe have started monitoring internal exposure to phthalates and its substitute 1,2-Cyclohexanedicarboxylic acid (DINCH), the comparability of results from…
Author: Henok Karvonen
Pre- and postnatal maternal depressive symptoms associate with white matter integrity in 5-year-olds in sex-specific manner
Biol Psychiatry. 2023 May 21:S0006-3223(23)01301-X. doi: 10.1016/j.biopsych.2023.05.014. Online ahead of print. ABSTRACT BACKGROUND: Pre- and postnatal maternal psychological distress predicts various detrimental consequences on social, behavioural, and cognitive development of the offspring and especially in girls. Maturation of white matter (WM) continues from prenatal development into adulthood and is thus…
Longitudinal consumption of fruits and vegetables and risk of asthma by 5 years of age
Pediatr Allergy Immunol. 2023 Mar;34(3):e13932. doi: 10.1111/pai.13932. ABSTRACT BACKGROUND: Fruit and vegetable consumption has been linked to a decreased risk of asthma, but prospective evidence on longitudinal consumption in childhood is scarce. We aimed to investigate the association between fruit and vegetable consumption in childhood and the risk of asthma…
Associations of active commuting to school in childhood and physical activity in adulthood
Sci Rep. 2023 May 11;13(1):7642. doi: 10.1038/s41598-023-33518-z. ABSTRACT This study examined whether active commuting to school in childhood and adolescence predicted active commuting to work and overall physical activity (PA) in adulthood. Participants from the Young Finns Study (N = 2436) were aged 9-18 years in 1980 and followed up…
Workplace Psychosocial Resources and Risk of Sleep Disturbances Among Employees
JAMA Netw Open. 2023 May 1;6(5):e2312514. doi: 10.1001/jamanetworkopen.2023.12514. ABSTRACT IMPORTANCE: Workplace psychosocial resources naturally tend to cluster in some work teams. To inform work-related sleep health promotion interventions, it is important to determine the associations between clustering of workplace resources and sleep disturbances when some resources are high while others…
Gene Set Based Integrated Methylome and Transcriptome Analysis Reveals Potential Molecular Mechanisms Linking Cigarette Smoking and Related Diseases
OMICS. 2023 May;27(5):193-204. doi: 10.1089/omi.2023.0028. Epub 2023 May 5. ABSTRACT Advanced integrative analysis of DNA methylation and transcriptomics data may provide deeper insights into smoke-induced epigenetic alterations, their effects on gene expression and related biological processes, linking cigarette smoking and related diseases. We hypothesize that accumulation of DNA methylation changes…
The relationship of trait-like compassion with epigenetic aging: The population-based prospective Young Finns Study
Front Psychiatry. 2023 Apr 18;14:1018797. doi: 10.3389/fpsyt.2023.1018797. eCollection 2023. ABSTRACT INTRODUCTION: Helping others within and beyond the family has been related to living a healthy and long life. Compassion is a prosocial personality trait characterized by concern for another person who is suffering and the motivation to help. The current…
Neighbourhood deprivation in childhood and adulthood and risk of arterial stiffness: the Cardiovascular Risk in Young Finns study
Blood Press. 2023 Dec;32(1):2220037. doi: 10.1080/08037051.2023.2220037. ABSTRACT Purpose: Individual socioeconomic status is associated with increased arterial stiffness, but limited data are available on the relations of neighbourhood deprivation with this vascular measure. We prospectively examined whether neighbourhood deprivation in childhood and adulthood predicts arterial stiffness indicated by pulse wave velocity…
Mother-infant interaction and maternal postnatal psychological distress are associated with negative emotional reactivity among infants and toddlers- A FinnBrain Birth Cohort study
Infant Behav Dev. 2023 Jun 5;72:101843. doi: 10.1016/j.infbeh.2023.101843. Online ahead of print. ABSTRACT Studies have reported mixed findings regarding the effects of mother-infant interaction and maternal distress on children’s negative emotional reactivity. In the current study (N = 134 and 107), we examined the effects of maternal Emotional Availability (sensitivity,…
Comorbidity in congenital hypothyroidism – A nationwide population-based cohort study
J Clin Endocrinol Metab. 2023 Jun 6:dgad334. doi: 10.1210/clinem/dgad334. Online ahead of print. ABSTRACT CONTEXT: Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties. OBJECTIVE: The aim of this nationwide population-based register study was to investigate the incidence of…
