Relationship of device measured physical activity type and posture with cardiometabolic health markers: pooled dose-response associations from the Prospective Physical Activity, Sitting and Sleep Consortium

Diabetologia. 2024 Mar 13. doi: 10.1007/s00125-024-06090-y. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: The aim of this study was to examine the dose-response associations of device-measured physical activity types and postures (sitting and standing time) with cardiometabolic health. METHODS: We conducted an individual participant harmonised meta-analysis of 12,095 adults (mean ±…

Are changes in sleep problems associated with changes in life satisfaction during the retirement transition?

Eur J Ageing. 2024 Mar 12;21(1):7. doi: 10.1007/s10433-024-00802-4. ABSTRACT Retirement reduces sleep problems, but changes in life satisfaction during the retirement transition are multifactorial and partly unknown. The aim of this prospective cohort study was to examine whether changes in sleep problems are associated with changes in total and domain-specific…

Association of childhood socioeconomic status with adulthood maximal exercise blood pressure: the Cardiovascular Risk in Young Finns Study

Blood Press. 2024 Dec;33(1):2323987. doi: 10.1080/08037051.2024.2323987. Epub 2024 Mar 11. ABSTRACT PURPOSE: Socioeconomic status has been related to resting blood pressure (BP) levels at different stages of life. However, the association of childhood socioeconomic status (SES) and adulthood exercise BP is largely unknown. Therefore, we studied the association of childhood…

Genome-wide characterization of circulating metabolic biomarkers

Nature. 2024 Mar 6. doi: 10.1038/s41586-024-07148-y. Online ahead of print. ABSTRACT Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism1-7. This detailed knowledge of the genetic determinants of systemic metabolism has been pivotal for uncovering how genetic pathways influence biological mechanisms…

Intergenerational continuity of loneliness and potential mechanisms: Young Finns Multigenerational Study

Sci Rep. 2024 Mar 5;14(1):5465. doi: 10.1038/s41598-024-56147-6. ABSTRACT Evidence on the intergenerational continuity of loneliness and on potential mechanisms that connect loneliness across successive generations is limited. We examined the association between loneliness of (G0) parents (859 mothers and 570 fathers, mean age 74 years) and their children (G1) (433…

A healthy lifestyle can support future sexual satisfaction: results from a 9-year longitudinal survey

J Sex Med. 2024 Mar 5:qdae009. doi: 10.1093/jsxmed/qdae009. Online ahead of print. ABSTRACT BACKGROUND: Previous follow-up studies have demonstrated the association between good health behavior and good sexual functioning for men, but the longitudinal relationship between multiple health behaviors and satisfaction with sex life remains understudied. AIM: The aim of…

Gene expression networks regulated by human personality

Mol Psychiatry. 2024 Mar 4. doi: 10.1038/s41380-024-02484-x. Online ahead of print. ABSTRACT Genome-wide association studies of human personality have been carried out, but transcription of the whole genome has not been studied in relation to personality in humans. We collected genome-wide expression profiles of adults to characterize the regulation of…

Longitudinal Associations between 24-H Movement Behaviors and Cardiometabolic Biomarkers: A Natural Experiment over Retirement

Med Sci Sports Exerc. 2024 Feb 29. doi: 10.1249/MSS.0000000000003415. Online ahead of print. ABSTRACT INTRODUCTION: Physical activity, sedentary behavior and sleep, that is, 24-h movement behaviors, often change in the transition from work to retirement, which may affect cardiometabolic health. This study investigates the longitudinal associations between changes in 24-h…

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