Genome Biol. 2024 Jan 16;25(1):22. doi: 10.1186/s13059-023-03136-z. ABSTRACT BACKGROUND: Pubertal growth patterns correlate with future health outcomes. However, the genetic mechanisms mediating growth trajectories remain largely unknown. Here, we modeled longitudinal height growth with Super-Imposition by Translation And Rotation (SITAR) growth curve analysis on ~ 56,000 trans-ancestry samples with repeated…
Publications
Publications
Association of long-term habitual dietary fiber intake since infancy with gut microbiota composition in young adulthood
J Nutr. 2024 Jan 12:S0022-3166(24)00027-0. doi: 10.1016/j.tjnut.2024.01.008. Online ahead of print. ABSTRACT BACKGROUND: Dietary fiber is an important health-promoting component of the diet, which is fermented by the gut microbes that produce metabolites beneficial for the host’s health. OBJECTIVE: We studied the associations of habitual long-term fiber intake from infancy…
Polygenic risk for depression predicting temperament trajectories over 15 years – A general population study
J Affect Disord. 2024 Jan 11:S0165-0327(24)00103-4. doi: 10.1016/j.jad.2024.01.093. Online ahead of print. ABSTRACT BACKGROUND: A great number of case-control and population-based studies have shown that depression patients differ from healthy controls in their temperament traits. We investigated whether polygenic risk for depression predicts trajectories of temperament traits from early adulthood…
Trajectories of maternal depressive and anxiety symptoms and child’s socio-emotional outcome during early childhood
J Affect Disord. 2024 Jan 4:S0165-0327(23)01544-6. doi: 10.1016/j.jad.2023.12.076. Online ahead of print. ABSTRACT Maternal symptoms of depression and anxiety during pregnancy and early postnatal years are suggested to impose differential negative effects on child’s socio-emotional development depending on the characteristics of the symptoms, such as timing, intensity, and persistence. The…
Climate Change, Summer Temperature, and Heat-Related Mortality in Finland: Multicohort Study with Projections for a Sustainable vs. Fossil-Fueled Future to 2050
Environ Health Perspect. 2023 Dec;131(12):127020. doi: 10.1289/EHP12080. Epub 2023 Dec 27. ABSTRACT BACKGROUND: Climate change scenarios illustrate various pathways in terms of global warming ranging from “sustainable development” (Shared Socioeconomic Pathway SSP1-1.9), the best-case scenario, to ‘fossil-fueled development’ (SSP5-8.5), the worst-case scenario. OBJECTIVES: We examined the extent to which increase…
Fruit, berry, and vegetable consumption and the risk of islet autoimmunity and type 1 diabetes in children – The DIPP birth cohort study
Am J Clin Nutr. 2023 Dec 22:S0002-9165(23)66347-6. doi: 10.1016/j.ajcnut.2023.12.014. Online ahead of print. ABSTRACT BACKGROUND: Prospective studies investigating the association between fruit, berry, and vegetable consumption and the risk of islet autoimmunity (IA) and type 1 diabetes (T1D) are few. OBJECTIVE: In this cohort study, we explored whether the consumption…
Association of number of siblings with preclinical markers of cardiovascular disease. The cardiovascular risk in Young Finns study
Int J Cardiol Cardiovasc Risk Prev. 2023 Dec 8;20:200227. doi: 10.1016/j.ijcrp.2023.200227. eCollection 2024 Mar. ABSTRACT To investigate the association of number of siblings with preclinical cardiovascular disease (CVD) markers in adulthood. The sample comprised 2776 participants (54 % female) from the Cardiovascular Risk in Young Finns Study who had CVD…
Finnish Retirement and Aging Study: a prospective cohort study
BMJ Open. 2023 Dec 10;13(12):e076976. doi: 10.1136/bmjopen-2023-076976. ABSTRACT PURPOSE: The Finnish Retirement and Aging (FIREA) Study was set up to study changes in health behavioural and cardiometabolic risk factors across retirement transition, and to examine the long-term consequences of work and retirement on health and functioning with advancing age. PARTICIPANTS:…
Sense of coherence, its components and depressive and anxiety symptoms in expecting women and their partners – A FinnBrain Birth Cohort Study
Sex Reprod Healthc. 2023 Nov 24;39:100930. doi: 10.1016/j.srhc.2023.100930. Online ahead of print. ABSTRACT OBJECTIVE: Expecting mothers with high sense of coherence (SOC) exhibit improved physical, emotional, and childbearing health. However, the dimensions of SOC and the factor structure of the SOC-13 scale during prenatal period is slightly known. Especially the…
Tracking of apolipoprotein B levels measured in childhood and adolescence: systematic review and meta-analysis
Eur J Pediatr. 2023 Dec 5. doi: 10.1007/s00431-023-05350-0. Online ahead of print. ABSTRACT To quantify the tracking of apolipoprotein B (apoB) levels from childhood and adolescence and compare the tracking of apoB with low-density lipoprotein (LDL) cholesterol, a systematic search of MEDLINE, Embase, Web of Science, and Google Scholar was…
