Sci Rep. 2023 Sep 24;13(1):15941. doi: 10.1038/s41598-023-43039-4. ABSTRACT Better understanding of the early events in the development of type 1 diabetes is needed to improve prediction and monitoring of the disease progression during the substantially heterogeneous presymptomatic period of the beta cell damaging process. To address this concern, we used…
Publications
Publications
Attention biases for emotional facial expressions during a free viewing task increase between 2.5 and 5 years of age
Dev Psychol. 2023 Sep 21. doi: 10.1037/dev0001598. Online ahead of print. ABSTRACT The normative, developmental changes in affect-biased attention during the preschool years are largely unknown. To investigate the attention bias for emotional versus neutral faces, an eye-tracking measurement and free viewing of paired pictures of facial expressions (i.e., happy,…
DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls
Autoimmunity. 2023 Dec;56(1):2259118. doi: 10.1080/08916934.2023.2259118. Epub 2023 Sep 19. ABSTRACT We elucidated the effect of four known T1D-susceptibility associated single nucleotide polymorphism (SNP) markers in three genes (rs12722495 and rs2104286 in IL2RA, rs689 in INS and rs2476601 in PTPN22) on CpG site methylation of their proximal promoters in different lymphocyte…
Maternal Perinatal Stress Trajectories and Negative Affect and Amygdala Development in Offspring
Am J Psychiatry. 2023 Sep 6:appiajp21111176. doi: 10.1176/appi.ajp.21111176. Online ahead of print. ABSTRACT OBJECTIVE: Maternal psychological stress during pregnancy is a common risk factor for psychiatric disorders in offspring, but little is known about how heterogeneity of stress trajectories during pregnancy affect brain systems and behavioral phenotypes in infancy. This…
Trajectories of COVID-19 pandemic-related depressive symptoms and potential predictors: the FinnBrain Birth Cohort Study
Soc Psychiatry Psychiatr Epidemiol. 2023 Sep 5. doi: 10.1007/s00127-023-02559-0. Online ahead of print. ABSTRACT PURPOSE: In the context of the COVID-19 pandemic, mental health problems have been reported, and parents of young children may be more vulnerable to psychological distress due to increased caregiving responsibilities. However, research on the heterogeneity…
Association of Tobacco Smoke Exposure with Metabolic Profile from Childhood to Early Adulthood. The Special Turku Coronary Risk Factor Intervention Project (STRIP)
Eur J Prev Cardiol. 2023 Sep 1:zwad285. doi: 10.1093/eurjpc/zwad285. Online ahead of print. ABSTRACT AIMS: To investigate the associations between passive tobacco smoke exposure and daily smoking with a comprehensive metabolic profile, measured repeatedly from childhood to adulthood. METHODS: Study cohort was derived from the Special Turku Coronary Risk Factor…
Effect of number of diffusion encoding directions in neonatal diffusion tensor imaging using Tract-Based Spatial Statistical analysis
Eur J Neurosci. 2023 Aug 29. doi: 10.1111/ejn.16135. Online ahead of print. ABSTRACT Diffusion tensor imaging (DTI) has been used to study the developing brain in early childhood, infants and in utero studies. In infants, number of used diffusion encoding directions has traditionally been smaller in earlier studies down to…
Do sleep problems explain the association between work stress and the trajectories of work ability from midlife to pensionable age?
J Occup Environ Med. 2023 Aug 28. doi: 10.1097/JOM.0000000000002954. Online ahead of print. ABSTRACT OBJECTIVE: This study examined whether mid-life work stress, defined as job strain and effort-reward imbalance (ERI), predicts work ability trajectories observed 12 years preceding the individual pensionable age. Additionally, the role of sleep problems as a…
Weekday and weekend physical activity patterns and their correlates among young adults
Scand J Med Sci Sports. 2023 Aug 25. doi: 10.1111/sms.14475. Online ahead of print. ABSTRACT BACKGROUND: Accelerometers enable assessment of within and between day variation in physical activity. The main aim was to examine weekday and weekend physical activity patterns among young adults. Additionally, correlates of the physical activity patterns…
Dietary Intake and Body Mass Index Influence the Risk of Islet Autoimmunity in Genetically At-Risk Children: A Mediation Analysis Using the TEDDY Cohort
Pediatr Diabetes. 2023;2023:3945064. doi: 10.1155/2023/3945064. Epub 2023 Feb 17. ABSTRACT BACKGROUND/OBJECTIVE: Growth and obesity have been associated with increased risk of islet autoimmunity (IA) and progression to type 1 diabetes. We aimed to estimate the effect of energy-yielding macronutrient intake on the development of IA through BMI. RESEARCH DESIGN AND…
