J Nutr. 2024 Sep 21:S0022-3166(24)01035-6. doi: 10.1016/j.tjnut.2024.09.018. Online ahead of print. ABSTRACT BACKGROUND: Prospective longitudinal evidence considering the entire childhood food consumption in relation to development of islet autoimmunity (IA or) type 1 diabetes is lacking. OBJECTIVES: We studied the associations of consumption of various foods and their combinations with…
Publications
Publications
Reciprocal relationships between a child’s engagement with faces and mother-child interaction at 8, 30, and 60 months
Dev Psychol. 2024 Sep 23. doi: 10.1037/dev0001831. Online ahead of print. ABSTRACT Prioritized attention to faces can be viewed as an early-developing marker of social engagement. This behavior is closely linked with early interactions, but there has been little research examining the longitudinal associations between social engagement and parent-child interaction.
Cognitive performance from childhood to old age and intergenerational correlations in the multigenerational Young Finns Study
J Neurol. 2024 Sep 22. doi: 10.1007/s00415-024-12693-7. Online ahead of print. ABSTRACT BACKGROUND: Cognitive performance changes during the lifespan, but the information is gathered from studies on separate age cohorts. Computerized neurocognitive testing enables efficient and similar assessments for all ages. We investigated (i) the effect of age at different…
Sleep duration and sleep loss during pregnancy: a longitudinal FinnBrain birth cohort study
Arch Gynecol Obstet. 2024 Sep 20. doi: 10.1007/s00404-024-07727-4. Online ahead of print. ABSTRACT PURPOSE: To investigate sleep duration and sleep loss during antenatal period and assess associative factors, including maternal characteristic and mood symptoms. METHODS: A cohort of 3038 women was enrolled. Self-reported sleep duration and sleep loss, the latter…
Early-pregnancy BMI, maternal gestational weight gain, and asthma and allergic diseases in children
Pediatr Allergy Immunol. 2024 Sep;35(9):e14240. doi: 10.1111/pai.14240. ABSTRACT BACKGROUND: Association of early pregnancy body mass index (BMI) and maternal gestational weight gain (GWG), and asthma and allergic disease in children is unclear. METHODS: We analyzed data from 3176 mother-child pairs in a prospective birth cohort study. Maternal anthropometric measurements in…
Life-period associations of body mass index with adult carotid intima-media thickness: The Bogalusa heart study and the cardiovascular risk in young Finns study
Prev Med. 2024 Sep 5:108128. doi: 10.1016/j.ypmed.2024.108128. Online ahead of print. ABSTRACT OBJECTIVE: Child and adult body mass index (BMI) associates with adult carotid artery intima-media thickness (cIMT). However, the relative contribution of BMI at different life-periods on adult cIMT has not been quantified. This study aimed to determine the…
A Clinical Tool to Relate Youth Risk Factors to Adult Cardiovascular Events and Type 2 Diabetes: The i3C Consortium
J Pediatr. 2024 Sep 2:114277. doi: 10.1016/j.jpeds.2024.114277. Online ahead of print. ABSTRACT OBJECTIVE: To translate data relating childhood cardiovascular (CV) risk factors and adult CV disease and type 2 diabetes mellitus (T2DM) to clinically actionable values. STUDY DESIGN: A prospective observational study (n=38,589) in the International Childhood Cardiovascular Cohort (i3C)…
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis
Nature. 2024 Sep 4. doi: 10.1038/s41586-024-07993-x. Online ahead of print. ABSTRACT Hyperlipidaemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD). Risk of cardiovascular events depends on cumulative lifetime exposure to low-density lipoprotein cholesterol (LDL-C) and, independently, on the time course of exposure to LDL-C, with early exposure being…
Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns
Epigenetics. 2024 Dec;19(1):2397297. doi: 10.1080/15592294.2024.2397297. Epub 2024 Sep 1. ABSTRACT Eastern and Western Finns show a striking difference in coronary heart disease-related mortality; genetics is a known contributor for this discrepancy. Here, we discuss the potential role of DNA methylation in mediating the discrepancy in cardiometabolic disease-risk phenotypes between the…
Osteosarcopenia in Finland: prevalence and associated factors
Arch Osteoporos. 2024 Aug 30;19(1):80. doi: 10.1007/s11657-024-01439-7. ABSTRACT This cross-sectional study investigated osteosarcopenia prevalence and its correlates among 2142 adults aged 55 and older in Finland. Findings show 3.9% had osteosarcopenia, while 13.8% and 11.1% had probable sarcopenia only or osteoporosis only, respectively. Osteosarcopenia was associated with low BMI, impaired…
