Cell Rep. 2024 Jul 3;43(7):114430. doi: 10.1016/j.celrep.2024.114430. Online ahead of print. ABSTRACT Cancer cells undergo major epigenetic alterations and transcriptomic changes, including ectopic expression of tissue- and cell-type-specific genes. Here, we show that the germline-specific RNA helicase DDX4 forms germ-granule-like cytoplasmic ribonucleoprotein granules in various human tumors, but not in…
Publications
Publications
Editorial: Update on epidemiology, endocrinology and treatment of cryptorchidism
Front Endocrinol (Lausanne). 2024 Jun 10;15:1435877. doi: 10.3389/fendo.2024.1435877. eCollection 2024. NO ABSTRACT PMID:38915895 | PMC:PMC11194432 | DOI:10.3389/fendo.2024.1435877…
Cardiovascular Risk Factors in Childhood and Adulthood and Cardiovascular Disease in Middle Age
JAMA Netw Open. 2024 Jun 3;7(6):e2418148. doi: 10.1001/jamanetworkopen.2024.18148. ABSTRACT IMPORTANCE: Recent evidence suggests that childhood levels of serum lipids, blood pressure, body mass index (BMI), and smoking contribute to adult risk of cardiovascular disease (CVD). Evidence is lacking on whether this is independent of adult risk levels. OBJECTIVE: To quantify…
Association of Serum Trimethylamine-N-Oxide Concentration from Childhood to Early Adulthood with Age and Sex
Clin Chem. 2024 Jun 22:hvae087. doi: 10.1093/clinchem/hvae087. Online ahead of print. ABSTRACT BACKGROUND: Primary prevention is the cornerstone of cardiometabolic health. In the randomized, controlled Special Turku Coronary Risk Factor Intervention Project (STRIP), dietary counseling intervention was given to children from infancy to 20 years of age and a follow-up…
Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child
Clin Nutr ESPEN. 2024 Aug;62:22-27. doi: 10.1016/j.clnesp.2024.05.001. Epub 2024 May 11. ABSTRACT BACKGROUND & AIMS: Maternal gluten intake in relation to child’s risk of type 1 diabetes has been studied in few prospective studies considering the diet during pregnancy but none during lactation. Our aim was to study whether gluten,…
The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study
J Endocr Soc. 2024 May 24;8(7):bvae103. doi: 10.1210/jendso/bvae103. eCollection 2024 May 23. ABSTRACT CONTEXT: The 2 peaks of type 1 diabetes incidence occur during early childhood and puberty. OBJECTIVE: We sought to better understand the relationship between puberty, islet autoimmunity, and type 1 diabetes. METHODS: The relationships between puberty, islet…
Change in cognitive performance during seven-year follow-up in midlife is associated with sex, age, and education – The Cardiovascular Risk in Young Finns Study
J Neurol. 2024 Jun 2. doi: 10.1007/s00415-024-12466-2. Online ahead of print. ABSTRACT OBJECTIVE: Sex, age, and education are associated with the level of cognitive performance. We investigated whether these factors modulate the change in cognitive performance in midlife by leveraging the longitudinal data from the Cardiovascular Risk in Young Finns…
Caesarean section and risk of type 1 diabetes
Diabetologia. 2024 May 31. doi: 10.1007/s00125-024-06176-7. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: Delivery by Caesarean section continues to rise globally and has been associated with the risk of developing type 1 diabetes and the rate of progression from pre-symptomatic stage 1 or 2 type 1 diabetes to symptomatic stage 3…
Does the effect of adolescent health behaviours on adult cardiometabolic health differ by socioeconomic background? Protocol for a population-based cohort study
BMJ Open. 2024 May 28;14(5):e078428. doi: 10.1136/bmjopen-2023-078428. ABSTRACT INTRODUCTION: Adolescence is a sensitive period for cardiometabolic health. Yet, it remains unknown if adolescent health behaviours, such as alcohol use, smoking, diet and physical activity, have differential effects across socioeconomic strata. Adopting a life-course perspective and a causal inference framework, we…
Determinants of echocardiographic epicardial adipose tissue in a general middle-aged population – The Cardiovascular Risk in Young Finns Study
Sci Rep. 2024 May 25;14(1):11982. doi: 10.1038/s41598-024-61727-7. ABSTRACT Epicardial adipose tissue (EAT) is the cardiac visceral fat depot proposed to play a role in the etiology of various cardiovascular disease outcomes. Little is known about EAT determinants in a general population. We examined cardiometabolic, dietary, lifestyle and socioeconomic determinants of…
