Extremely Early Appearance of Islet Autoantibodies in Genetically Susceptible Children

Pediatr Diabetes. 2023 Dec 11;2023:9973135. doi: 10.1155/2023/9973135. eCollection 2023. ABSTRACT OBJECTIVE: We studied the characteristics of children who developed islet autoantibodies by the age of 0.50 years and hypothesized that the appearance of extremely early islet autoimmunity differs between four birth cohorts within 1994-2019 according to the change in the…

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Regulation of nc886 (vtRNA2-1) RNAs is associated with cardiometabolic risk factors and diseases

Clin Epigenetics. 2025 Apr 29;17(1):68. doi: 10.1186/s13148-025-01871-7. ABSTRACT Non-coding 886 (nc886, vtRNA2-1) is a polymorphically imprinted gene. The methylation status of this locus has been shown to be associated with periconceptional conditions, and both the methylation status and the levels of nc886 RNAs have been shown to associate with later-life…

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Association of multimorbidity with working life expectancy among adults aged 50 years and older: Findings from two prospective cohort studies

J Multimorb Comorb. 2025 Apr 15;15:26335565251331187. doi: 10.1177/26335565251331187. eCollection 2025 Jan-Dec. ABSTRACT BACKGROUND: Individual diseases are important risk factors for early exit from the labour force among older adults, but the contribution of multimorbidity to working life expectancy (WLE) is unclear. METHODS: We used data from two prospective cohort studies:…

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Measuring adverse childhood experiences by interviewing children at 9 and 10 years of age: Prevalence, concordance with mother-reports, posttraumatic stress disorder symptoms, and subjective experience of being asked about adverse childhood experiences in FinnBrain Birth cohort study

J Exp Child Psychol. 2025 Apr 18;256:106238. doi: 10.1016/j.jecp.2025.106238. Online ahead of print. ABSTRACT How children experience the screening of adverse childhood experiences (ACEs) is little studied. Moreover, the similarity between parental and child reports is unknown. We interviewed 9-year-olds (a subsample of the FinnBrain Birth Cohort Study; N =…

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Impact of retirement transition on health, well-being and health behaviours: critical insights from an overview of reviews

Soc Sci Med. 2025 Apr 3;375:118049. doi: 10.1016/j.socscimed.2025.118049. Online ahead of print. ABSTRACT Retirement is a pivotal life course transition wich may have profound implications for health, well-being and health behaviours. Despite extensive research and theoretical debate, the impact of retirement on health remains inconclusive, with studies reporting positive, negative,…

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Infant Subcortical Brain Volumes Associated with Maternal Obesity and Diabetes: A Large Multicohort Study

medRxiv [Preprint]. 2025 Mar 27:2025.03.25.25324641. doi: 10.1101/2025.03.25.25324641. ABSTRACT IMPORTANCE: Maternal diabetes (MD) and maternal obesity (MO) have been robustly established to confer health risks in offspring. Additionally, mounting evidence suggests that these fetal programming effects vary by sex, but whether these factors independently or interactively influence infant brain development remains…

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Changes in Oral Health-Related Quality of Life According to Public Oral Health Procedures in Parents of Young Children From the FinnBrain Birth Cohort Study

Community Dent Oral Epidemiol. 2025 Apr 4. doi: 10.1111/cdoe.13039. Online ahead of print. ABSTRACT OBJECTIVES: The aim was to evaluate the association between public oral healthcare procedures and change in oral health-related quality of life (OHRQoL) over 4 years among parents in the FinnBrain Cohort Study, comparing those who did…

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