Maternal prenatal depressive symptoms and child brain responses to affective touch at two years of age

J Affect Disord. 2024 Mar 18:S0165-0327(24)00515-9. doi: 10.1016/j.jad.2024.03.092. Online ahead of print. ABSTRACT BACKGROUND: Touch is an essential form of mother-child interaction, instigating better social bonding and emotional stability. METHODS: We used diffuse optical tomography to explore the relationship between total haemoglobin (HbT) responses to affective touch in the child’s…

Deteriorating Semen Quality: The Role of the Environment

Semin Reprod Med. 2023 Nov;41(6):226-240. doi: 10.1055/s-0044-1782151. Epub 2024 Mar 18. ABSTRACT Since the end of the last century, several reports have suggested that semen quality is declining, especially in Western countries. Furthermore, cross-sectional studies using similar protocols have suggested regional differences in semen quality of young and fertile men.

A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations

medRxiv [Preprint]. 2024 Mar 8:2024.03.07.24303870. doi: 10.1101/2024.03.07.24303870. ABSTRACT Although both short and long sleep duration are associated with elevated hypertension risk, our understanding of their interplay with biological pathways governing blood pressure remains limited. To address this, we carried out genome-wide cross-population gene-by-short-sleep and long-sleep duration interaction analyses for three…

Pubertal testicular volume references for ruler, orchidometer, and ultrasonography measurements based on a longitudinal follow-up

Andrology. 2024 Mar 14. doi: 10.1111/andr.13629. Online ahead of print. ABSTRACT BACKGROUND: Testicular volume is a marker of male pubertal development. Various clinical conditions and their treatments may influence testicular growth. OBJECTIVES: To create ruler-based age-dependent pubertal testicular volume references that enable calculation of standard deviation (SD) scores. MATERIALS AND…

Relationship of device measured physical activity type and posture with cardiometabolic health markers: pooled dose-response associations from the Prospective Physical Activity, Sitting and Sleep Consortium

Diabetologia. 2024 Mar 13. doi: 10.1007/s00125-024-06090-y. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: The aim of this study was to examine the dose-response associations of device-measured physical activity types and postures (sitting and standing time) with cardiometabolic health. METHODS: We conducted an individual participant harmonised meta-analysis of 12,095 adults (mean ±…

Are changes in sleep problems associated with changes in life satisfaction during the retirement transition?

Eur J Ageing. 2024 Mar 12;21(1):7. doi: 10.1007/s10433-024-00802-4. ABSTRACT Retirement reduces sleep problems, but changes in life satisfaction during the retirement transition are multifactorial and partly unknown. The aim of this prospective cohort study was to examine whether changes in sleep problems are associated with changes in total and domain-specific…

Association of childhood socioeconomic status with adulthood maximal exercise blood pressure: the Cardiovascular Risk in Young Finns Study

Blood Press. 2024 Dec;33(1):2323987. doi: 10.1080/08037051.2024.2323987. Epub 2024 Mar 11. ABSTRACT PURPOSE: Socioeconomic status has been related to resting blood pressure (BP) levels at different stages of life. However, the association of childhood socioeconomic status (SES) and adulthood exercise BP is largely unknown. Therefore, we studied the association of childhood…

Genome-wide characterization of circulating metabolic biomarkers

Nature. 2024 Mar 6. doi: 10.1038/s41586-024-07148-y. Online ahead of print. ABSTRACT Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism1-7. This detailed knowledge of the genetic determinants of systemic metabolism has been pivotal for uncovering how genetic pathways influence biological mechanisms…

Intergenerational continuity of loneliness and potential mechanisms: Young Finns Multigenerational Study

Sci Rep. 2024 Mar 5;14(1):5465. doi: 10.1038/s41598-024-56147-6. ABSTRACT Evidence on the intergenerational continuity of loneliness and on potential mechanisms that connect loneliness across successive generations is limited. We examined the association between loneliness of (G0) parents (859 mothers and 570 fathers, mean age 74 years) and their children (G1) (433…

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